Ph.D.: 2000 Purdue University
Postdoctoral: Purdue University
Postdoctoral: Texas A&M University

The Proteome Anlaysis Laboratory is a core facility located in Health Sciences 221 on the Wright State University Main Campus. Users may sign up for time on various instruments through the iLab organizer. To obtain a user account, please contact Dr. David Cool.

Users of the proteomics laboratory may find the following manuals to be helpful:

Azure Cielo qPCR machine

Bio Rad ChemiDOC MP+ Imager

BioTek Synergy H1 Plate Reader

Sorvall LYNX 4000 Centrifuge

Sorvall MX 120+ micro-Ultracentrifuge

1. Rider, S. D. Jr., Owens, M. S., Rohan, C. A., Travers, J. B., & Kemp, M. G. (2025). Translesion DNA synthesis gene expression is dysregulated in ultraviolet-irradiated geriatric skin. JID Innovations 5(6), 100409.
2. Gadgil, R. Y., Rider, S. D. Jr., Shrestha, R., Alhawach, V., Hitch, D., & Leffak, M. (2024). Microsatellite break-induced replication generates highly mutagenized extrachromosomal circular DNAs. NAR Cancer, 6(2), zcae027.
3. Cvammen, W., Rider, S. D. Jr., & Kemp, M. G. (2024). Analysis of circadian clock gene expression in epidermal human skin indicates that body location impacts rhythm amplitude. The Journal of Investigative Dermatology. Advance online publication. https://doi.org/10.1016/j.jid.2024.05.010
4. Cvammen, W., Rider, S. D. Jr., Travers, J. B., & Kemp, M. G. (2024). Effects of age and sex on the expression of core circadian clock genes in human skin epidermis. The Journal of Investigative Dermatology, 144(5), 1172–1175.
5. Rider, S. D. Jr. (2023). The genome of the Blue Death-Feigning Beetle, Asbolus verrucosus LeConte, 1851 (Coleoptera: Tenebrionidae). The Coleopterists Bulletin, 77(4), 481–500.
6. Rider, S. D. Jr., Damewood, F. J. IV, Gadgil, R. Y., Hitch, D. C., Alhawach, V., Shrestha, R., Shanahan, M., Zavada, N., & Leffak, M. (2023). Suppressors of break-induced replication in human cells. Genes, 14(2), 398.
7. Rider, S. D. Jr., & Hostetler, H. A. (2022). Reflex bleeding in tonically immobilized larvae causes debris-based camouflage in the Blue Death-Feigning Beetle, Asbolus verrucosus LeConte (Coleoptera: Tenebrionidae). The Coleopterists Bulletin, 76(2), 237–247.
8. Rider, S. D. Jr., Gadgil, R. Y., Hitch, D. C., Damewood, F. J. IV, Zavada, N., Shanahan, M., Alhawach, V., Shrestha, R., Shin-Ya, K., & Leffak, M. (2022). Stable G-quadruplex DNA structures promote replication-dependent genome instability. Journal of Biological Chemistry, 298(6), 101947.
9. Alghamri, M. S., Sharma, P., Williamson, T. L., Readler, J. M., Yan, R., Rider, S. D. Jr., Hostetler, H. A., Cool, D. R., Kolawole, A. O., & Excoffon, K. J. D. A. (2021). MAGI-1 PDZ2 domain blockade averts adenovirus infection via enhanced proteolysis of the apical coxsackievirus and adenovirus receptor. Journal of Virology, 95(13), e0004621.
10. Gadgil, R. Y., Romer, E. J., Goodman, C. C., Rider, S. D. Jr., Damewood, F. J. IV, Barthelemy, J. R., Shin-Ya, K., Hanenberg, H., & Leffak, M. (2020). Replication stress at microsatellites causes DNA double-strand breaks and break-induced replication. Journal of Biological Chemistry, 295(45), 15378–15397.
11. Gadgil, R. Y., Rider, S. D. Jr., Lewis, T., Barthelemy, J., & Leffak, M. (2020). Analysis of trinucleotide repeat stability by integration at a chromosomal ectopic site. In Methods in Molecular Biology (Vol. 2056, pp. 121–136).
12. Rider, S. D. Jr., Morgan, M. S., & Arlian, L. G. (2017). Allergen homologs in the Euroglyphus maynei draft genome. PLoS One, 12(8), e0183535.
13. Morgan, M. S., Rider, S. D. Jr., & Arlian, L. G. (2017). Identification of antigenic Sarcoptes scabiei proteins for use in a diagnostic test and of non-antigenic proteins that may be immunomodulatory. PLoS Neglected Tropical Diseases, 11(6), e0005669.
14. Bedi, S., Hostetler, H. A., & Rider, S. D. (2017). Mutations in liver X receptor alpha that selectively impair dimerization and ligand dependent transactivation. Nuclear Receptor Research, 4, 101302. https://doi.org/10.11131/2017/101302
15. Bedi, S., Hines, G. V., Lozada-Fernandez, V. V., de Jesus Piva, C., Kaliappan, A., Rider, S. D., & Hostetler, H. A. (2017). Fatty acid binding profile of the liver X receptor α. Journal of Lipid Research, 58(2), 393–402.
16. Ogburn, R. N., Randall, T. A., Xu, Y., Roberts, J. H., Mebrahtu, B., Karnuta, J. M., Rider, S. D., Kissling, G. E., London, R. E., Pomés, A., Arlian, L., Fitzgerald, M. C., & Mueller, G. A. (2016). Are dust mite allergens more abundant and/or more stable than other Dermatophagoides pteronyssinus proteins? Journal of Allergy and Clinical Immunology. https://doi.org/10.1016/j.jaci.2016.08.016
17. Arlian, L. G., Morgan, M. S., & Rider, S. D. (2016). Sarcoptes scabiei: Genomics to proteomics to biology. Parasites & Vectors, 9(1), 380.
18. Morgan, M. S., Arlian, L. G., Rider, S. D. Jr., Grunwald, W. C. Jr., & Cool, D. R. (2016). A proteomic analysis of Sarcoptes scabiei (Acari: Sarcoptidae). Journal of Medical Entomology, 53(3), 553–561.
19. Rider, S. D. Jr., Morgan, M. S., & Arlian, L. G. (2016). Draft genome of the scabies mite. Parasites & Vectors, 8(1), 1–14.
20. Rider, S. D. Jr. (2015). The complete mitochondrial genome of the desert darkling beetle Asbolus verrucosus (Coleoptera, Tenebrionidae). Mitochondrial DNA, 27(4), 2824-2826.
21. Balanarasimha, M., Oswal, D. P., Soman, F., Rider, S. D. Jr., & Hostetler, H. A. (2014). Ligand-regulated heterodimerization of peroxisome proliferator-activated receptor α with liver X receptor α. Biochemistry, 53(16), 2632–2643.
22. Oswal, D. P., Alter, G. M., Rider, S. D. Jr., & Hostetler, H. A. (2014). A single amino acid change humanizes long-chain fatty acid binding and activation of mouse peroxisome proliferator-activated receptor α. Journal of Molecular Graphics and Modeling, 51, 27–36.
23. Guo, F., Zhang, H., Fritzler, J. M., Rider, S. D. Jr., Xiang, L., McNaire, N. N., Mead, J. R., & Zhu, G. (2013). Amelioration of Cryptosporidium parvum infection in vitro and in vivo by targeting parasite fatty acyl-CoA synthetases. Journal of Infectious Diseases, 209(8), 1279–1287.
24. Oswal, D. P., Balanarasimha, M., Loyer, J. K., Bedi, S., Soman, F. L., Rider, S. D. Jr., & Hostetler, H. A. (2013). Divergence between human and murine peroxisome proliferator-activated receptor alpha ligand specificities. Journal of Lipid Research, 54(9), 2354–2365.
25. Kroemer, J. A., Coates, B. S., Nusawardani, T., Rider, S. D. Jr., Fraser, L. M., & Hellmich, R. L. (2011). A rearrangement of the Z chromosome topology influences the sex-linked gene display in the European corn borer, Ostrinia nubilalis. Molecular Genetics and Genomics, 286(1), 37–56.
26. Lei, C., Rider, S. D. Jr., Wang, C., Zhang, H., Tan, X., & Zhu, G. (2010). The apicomplexan Cryptosporidium parvum possesses a single mitochondrial-type ferredoxin and ferredoxin: NADP+ reductase system. Protein Science, 19(11), 2073–2084.
27. Rider, S. D. Jr., Srinivasan, D. G., & Hilgarth, R. S. (2010). Chromatin-remodelling proteins of the pea aphid, Acyrthosiphon pisum (Harris). Insect Molecular Biology, 19(S2), 201–214.
28. International Aphid Genomics Consortium (includes Rider, S. D. Jr.). (2010). Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS Biology, 8(1), e1000313.
29. Ramsey, J. S., Rider, D. S., Walsh, T. K., De Vos, M., Gordon, K. H. J., Ponnala, S. L., Macmil, S., Roe, B. A., & Jander, G. (2010). Comparative analysis of detoxification enzymes in Acrythosiphon pisum and Myzus persicae. Insect Molecular Biology, 19(S2), 155–164.
30. Rider, S. D. Jr., & Zhu, G. (2010). Cryptosporidium: Genomic and biochemical features. Experimental Parasitology, 124(1), 2–9.
31. Rider, S. D. Jr., & Zhu, G. (2008). An Apicomplexan ankyrin repeat histone deacetylase with relatives in photosynthetic eukaryotes. International Journal for Parasitology, 39(6), 747–754.
32. Rider, S. D. Jr., & Zhu, G. (2008). Differential expression of the two distinct replication protein A subunits from Cryptosporidium parvum. Journal of Cellular Biochemistry, 104(6), 2207–2216.
33. Zhang, H., Rider, S. D. Jr., Henderson, J. T., Fountain, M., Chuang, K., Kandachar, V., Simons, A., Jerome, R. J., Edenberg, H. J., Romero-Severson, J., Muir, W. M., & Ogas, J. P. (2008). The CHD3 remodeler PICKLE promotes trimethylation of histone H3 lysine 27. Journal of Biological Chemistry, 283(32), 22637–22648.
34. Muir, W. M., Rosa, G. J. M., Pittendrigh, B. R., Xu, S., Rider, S. D., Fountain, M., & Ogas, J. (2008). A mixture model approach for the analysis of small exploratory microarray experiments. Computational Statistics & Data Analysis, 53(5), 1566–1576.
35. Rider, S. D. Jr., & Zhu, G. (2007). Apicomplexans - Cryptosporidium spp. In N. A. Khan (Ed.), Emerging protozoan pathogens (pp. 193–225). Taylor & Francis.
36. Muir, W. M., Romero-Severson, J., Rider, S. D. Jr., Simons, A., & Ogas, J. (2006). Application of one-sided t-tests and a generalized experiment wise error rate to high-density oligonucleotide microarray experiments: An example using Arabidopsis. Journal of Data Science, 4(3), 323–341.
37. Li, H. C., Chuang, K., Henderson, J. T., Rider, S. D. Jr., Bai, Y., Zhang, H., Fountain, M., Gerber, J., & Ogas, J. (2005). PICKLE acts during germination to repress expression of embryonic traits. Plant Journal, 44(6), 1010–1022.
38. Rider, S. D. Jr., Cai, X. M., Sullivan, W. J. Jr., Smith, A. T., Radke, J., White, M., & Zhu, G. (2005). The protozoan parasite Cryptosporidium parvum possesses two functionally and evolutionarily divergent replication protein A large subunits. Journal of Biological Chemistry, 280(36), 31460–31469.
39. Hemm, M. R., Rider, S. D., Ogas, J., Murray, D. J., & Chapple, C. (2004). Light induces phenylpropanoid metabolism in Arabidopsis roots. Plant Journal, 38(5), 765–778.
40. Behura, S., Valicente, F. H., Rider, S. D. Jr., Shun-Chen, M., Jackson, S., & Stuart, J. J. (2004). Recombination suppression in the Hessian fly revealed by a genetic linkage map and linkage to avirulence. Genetics, 167(1), 343–355.
41. Rider, S. D. Jr., Hemm, M. R., Hostetler, H. A., Chapple, C., & Ogas, J. (2004). Metabolic profiling of the Arabidopsis pkl mutant reveals selective derepression of embryonic traits. Planta, 219(3), 489–499.
42. Henderson, J. T., Li, H. C., Rider, S. D., Mordhorst, A. P., Romero-Severson, J., Cheng, J. C., Robey, J., Sung, Z. R., de Vries, S. C., & Ogas, J. (2003). PICKLE acts throughout the plant to repress expression of embryonic traits and may play a role in gibberellin-dependent responses. Plant Physiology, 134(3), 995–1005.
43. Rider, S. D. Jr., Henderson, J. T., Jerome, R. J., Romero-Severson, J., Edenberg, H. J., & Ogas, J. P. (2003). Coordinate repression of regulators of embryonic identity by PICKLE during germination in Arabidopsis. Plant Journal, 35(1), 33–43.
44. Rider, S. D. Jr., Sun, W., Ratcliffe, R. H., & Stuart, J. J. (2002). Chromosome landing near avirulence gene vH13 in the Hessian fly. Genome, 45(5), 812–822.
45. Rider, S. D. Jr., Sun, W., Ratcliffe, R. H., and Stuart, J. J. (2000). Hessian Fly Map. Annual Wheat Newsletter, 46, 184.
46. Schulte, S. J., Rider, S. D. Jr., Hatchett, J. H., & Stuart, J. J. (1999). Molecular genetic mapping of three X-linked avirulence genes, vH6, vH9, vH13 in the Hessian fly. Genome, 42(5), 821–828.
47. Rider, S. D. Jr., Wilde, G. E., & Kambhampati, S. (1998). Genetics of esterase-mediated insecticide resistance in the aphid Schizaphis graminum. Heredity, 81(1), 14–19.
48. Rider, S. D. Jr., & Wilde, G. E. (1998). Variation in fecundity and sexual morph production among insecticide resistant clones of the aphid Schizaphis graminum. Journal of Economic Entomology, 91(2), 388–391.
49. Rider, S. D. Jr., Dobesh, S. M., & Wilde, G. E. (1998). Insecticide resistance in a novel laboratory-produced greenbug (Homoptera: Aphididae) clone. Journal of Economic Entomology, 91(1), 30–33.
50. Rider, S. D. Jr. (1997). Biological significance, genetic mechanism, and potential of esterase-mediated insecticide resistance in the greenbug. Resistant Pest Management Newsletter, 9(1), 8–10.