Andrew Alvin Voss, Ph.D.

Biological Sciences
Associate Professor
Biological Sciences II 056, 3640 Colonel Glenn Hwy, Dayton, OH 45435-0001

Previous Positions and Education

Assistant Professor, California State Polytechnic University, Pomona


  • Postdoctoral Fellow, Physiology, UCLA David Geffen School of Medicine (Advisors: Ernest M. Wright and Julio L. Vergara)
  • Ph.D., Pharmacology and Toxicology, University of California, Davis (Advisor: Isaac N. Pessah of School of Vet Med)
  • Teaching Credential, National University, Sacramento, California
  • B.S., Biochemistry, University of California, Davis
  • Transfer Student, American River Community College, Sacramento, California



Courses Taught

Wright State University

  • Neuromuscular Physiology (BIO4020)
  • Cell Biology & Physiology (BIO4030)
  • Cell Biology (BIO7300)

Cal Poly Pomona

  • Human Physiology (BIO235/L formerly ZOO235/L)
  • Neuromuscular Physiology (BIO575)
  • Animal Models & Muscle Disease (BIO575)
  • Basic Biology (BIO115)

Research Statement

My laboratory examines skeletal muscle and muscle physiology using electrophysiology, pharmacology, biochemistry, and optics. We are currently working on muscle dysfunction in Huntington's disease and purniergic signaling.  With some outstanding collaborators, our research on individual muscle fibers and molecular mechanisms extends to whole animal behavior and the clinic.  Collaborators include Drs. Robert Talmadge and Andrew Steele of Cal Poly Pomona, Dr. Mark Rich of Wright State University, and Drs Sandra Kostyk and Miriam Freimer of the Ohio State University Movement Disorders Division.

We always want to hear from students and postdocs interested in the lab. Currently, there is an opening for a postodoctoral scholar.

Some Publications (*Undergraduate Student, **Graduate Student)

  1. Ahmed Hawash, Andrew A. Voss (co-corr auth), and Mark M. Rich (co-corr auth). Inhibiting persistent inward sodium currents prevents myotonia. Annals of Neurology. 2017 in press Epub, Early Release.
  2. Ahmad Khedraki**, Eric J. Reed**, Shannon H. Romer, Qingbo Wang, William Romine, Mark M. Rich, Robert J. Talmadge, and Andrew A. Voss (corr auth). Depressed Synaptic Transmission and Reduced Vesicle Release Sites in Huntington's Disease Neuromuscular Junctions. Journal of Neuroscience. 2017 Aug 23, 37(34):8077-91.

This article was featured on the cover of the Aug. 23 issue.

  1. Daniel R. Miranda**, Monica Wong**, Shannon H. Romer, Cynthia McKee*, Gabriela Garza-Vasquez*, Alyssa C. Medina*, Volker Bahn, Andrew D. Steele, Robert J. Talmadge, and Andrew A. Voss (corr auth). Progressive Cl channel defects reveal disrupted skeletal muscle maturation in R6/2 Huntington’s mice. Journal of General Physiology. 2017 Jan;149(1) 55-74.

Highlighted with a Commentary, Martin Skov and Robert T. Dirksen. Trojan triplets: RNA-based pathomechanisms for muscle dysfunction in Huntington’s disease. Journal of General Physiology. 2017 Jan;149(1) 49-53.

  1. Donald Beqollari, Christian F. Romberg, Gabriella Dobrowolny, Martina Martini, Andrew A. Voss, Antonio Musarò, and Roger A. Bannister. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis. Skeletal Muscle. 2016 Jun 23;6:24.
  2. **Christopher W. Waters, *Grigor Varuzhanyan, Robert J. Talmadge, and Andrew A. Voss (corr auth). Huntington’s disease skeletal muscle is hyperexcitable owing to chloride and potassium channel dysfunction. Proceedings of the National Academy of Sciences. 2013 May;110(22): 9160-65.

Faculty of 1000 Recommendation

  1. Charles S. Hummel, C Lu, Donald D. Lu, Bruce Hirayama, Andrew A. Voss and Ernest M. Wright.  Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.  American Journal of Physiology – Cell Physiology. 2011 Jan;300(1):C14-21.

Faculty of 1000 Recommendation

  1. Andrew A. Voss (corr auth). Extracellular ATP inhibits chloride channels in mature mammalian skeletal muscle by activating P2Y1 receptors.  Journal of Physiology-London. 2009 587: 5739-5752.
  2. Andrew A. Voss, Paul D. Allen, Isaac N. Pessah and Claudio F. Perez.  Allosterically coupled calcium and magnesium binding sites are unmasked by ryanodine receptor chimeras.  Biochemical and Biophysical Research Communications. 2008 Feb;366: 988-93.
  3. Andrew A. Voss (corr auth), Ana Diez-Sampedro, Bruce Hirayama, Donald D.F. Loo and Ernest M. Wright.  Imino sugars are potent agonists of the human glucose sensor SGLT3.  Molecular Pharmacology.  2007 Feb;71(2):628-634.
  4. Jun Gao, Andrew A. Voss, Isaac N. Pessah, Fredine Lauer, Trevor Penning and Scott W. Burchiel.  Ryanodine receptor-mediated rapid increase in intracellular calcium induced by 7,8-benzo(a)pyrene quinone in human and murine leukocytes. Toxicological Sciences. 2005 Oct;87(2):419-426.
  5. Andrew A. Voss, Jozsef Lango, Michael Ernst-Russell, Dexter Morin and Isaac N. Pessah.  Identity of redox-sensitive hyperreactive cysteines within ryanodine receptor type 1.  The Journal of Biological Chemistry. 2004 Aug;279(33):34514-20.
  6. Claudio F. Perez, Andrew A. Voss, Isaac N. Pessah and Paul D. Allen.  RyR1/RyR3 chimeras reveal that multiple domains of RyR1 are involved in skeletal-type E-C coupling. Biophysical Journal. 2003 Apr;84(4):2655-63.
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