David A. Grossie, Ph.D.

Department:
Chemistry
Title:
Chair and Associate Professor of Chemistry
Address:
Oelman Hall 202, 3640 Colonel Glenn Hwy., Dayton, OH 45435-0001

Dr. Grossie received his BS in chemistry from Texas Lutheran College in 1977, and his PhD from Texas Christian University in 1982.  Subsequently, Dr. Grossie was a postdoctoral research associate at Baylor University.

From 2001 until 2012  he served as Assistant Chair of the Department of Chemistry, and became Chair in 2012.

Since joining the Faculty at Wright State University, Dr. Grossie chaired the COSM Computing & Technology Committee and was a member of the Science Lab Renovations Committee, University Technology Committee, and University Classrooms of the Future Committee.  He was also involved in the development of networking and technology plans for the University. 

External to the University, Dr. Grossie served on the OARNet Faculty Advisory Committee and the Patterson-Crane Committee of the Dayton Section of the American Chemical Society.

During the summers of 1987 and 1989, Dr. Grossie was a visiting scientist at the Non-Metallic Materials Directorate of Wright Laboratories, Wright-Patterson AFB

Dr. Grossie holds memberships in the American Chemical Society, American Crystallographic Association, International Union of Crystallography, and American Institute of Physics.

Formally trained in inorganic chemistry, Dr. Grossie describes himself as a structural chemist.  With expertise in X-ray diffraction and crystallography, his current research is in examination of the structure of crystalline compounds and the relationship between the structure and its properties.  His latest projects have involved the structure of dilithium phthalocyanates, the structure of helical or otherwise non-planar aromatic systems, the structure and stability of syndones and their derivatives,and substitution patterns in N-substituted pyrroles.  

Dr. Grossie has been a co-author or lead author on 50 publications, has presented 39 oral or poster presentations, and has co-editted 7 editions of a “Laboratory Guide for Chemistry.”

An associated interest in the beginning of his career was the development of crystallographic software for small, low cost computer systems.  In collaboration with researchers in Maryland and Australia, Dr. Grossie developed software for IBM PC compatibles for the tedious calculations involved in x‑ray crystallography.  This software gained an international reputation with distribution to scientists in 25 countries, and helped demonstrate that small molecule x-ray crystallographic calculations on a personal computer could be cost effective in the modern diffraction laboratory.

Education History: 

Bachelor of Science - Texas Lutheran College (1977).

Doctorate of Philosophy in Chemistry - Texas Christian University (1982).

Postdoctoral - Department of Chemistry, Texas Christian University (1982) with Professor William H. Watson

Postdoctoral - Department of Chemistry, Baylor University (1982 - 1986) with Professors W. O. Milligan and Donald Mullica.

Academics

Research statement: 

Research efforts in my group are being carried out in the area of single-crystal x-ray diffraction to examine a variety of materials, such as:

  • polymer precursers and pendants with interest in their non-linear optical properties.
  • sydnones.
  • crystalline battery substrates.
  • novel organic and inorganic molecules

Professional

Publications: 

M. Node, M. Sai, K. Fuji, E. Fujita, T. Shingu, W. H. Watson, and David A. Grossie, "Three New Anti‑Tumor Diterpenoids, Trichorabdals A, C, and D," Chemistry Letters, 2023‑26 (1982).

David A. Grossie, W. H. Watson, F. Vogtle, and W. M. Muller, "A 1,4,7,10,13,16‑ Hexaoxacyclooctadecane(18‑crown‑6)‑4,4'‑Biphenyldiol Dihydrate Ternary Complex," Acta Crystallogr., B38, 3157‑59 (1982).

W. H. Watson, David A. Grossie, and I. F. Taylor, Jr., "9,9'‑Bisbicyclo‑ [3.3.1]nonylidene," Acta Crystallogr., B38, 3159‑61 (1982).

W. H. Watson, David A. Grossie, F. Vogtle, and W. M. Muller, "Aquabis(2,2'‑bipyridyl)-bis(thiocyanato‑N)‑calcium, Ca(C10H8N2)2(SCN)2*H2O, and Catena‑bis(2,2'‑bipyridyl)‑ bis‑‑(thiocynato‑S,N)‑barium, B a(C10H8N2)2(SCN)2,"  Acta Crystallogr., C39, 720‑23 (1983).

W. O. Milligan, D. F. Mullica, David A. Grossie, and C. K. C. Lok, "Crystal Structure of Yb(OH)3," J. Solid State Chem., 50, 129‑32 (1983).

W. H. Watson, J. Galloy, David A. Grossie, and J. Nakayama,"2‑(1,3‑Dithiol‑2­ylidene)‑4‑cyclopentene‑1,3‑dione, C8H4O2S2, and 2‑(1,3‑Benzodithiol‑2‑ylidene)­cyclohexanone, C13H12OS2," Acta Crystallogr., C40, 190‑93 (1984).

W. H. Watson, J. Galloy, David A. Grossie, F. Vogtle, and W. M. Muller, "Host‑Guest Complex Chemistry: Structures of 18‑Crown‑6 and Diaza‑18‑crown‑6 with Neutral Molecules," J. Org. Chem., 49, 347‑53 (1984).

R. P. Kashyap, W. H. Watson, David A. Grossie, M. Node, M. Sai, E. Fujita, and K. Fuji, "Trichorabdal F Acetate, C22H28O7," Acta Crystallogr., C40, 515‑17 (1984).

W. O. Milligan, D. F. Mullica, H. O. Perkins, David A. Grossie, and C. K. C. Lok, "Idealized Eleven‑Coordinate Geometries," Inorg. Chim. Acta, 86, 33‑36 (1984).

W. H. Watson, J. Galloy, David A. Grossie, P. D. Bartlett, and G. L. Combs, "1,2,3,4,9,10­‑Hexahydro‑9,10‑exo‑epoxy‑1,4‑exo‑methanthracene (1) (syn‑oxa‑benzo­sesquinorbornene), C15H14O, and Adducts with Dichlorocarbene (2), C16H14Cl2O, and Anthranilic Acid, C23H24O6*2(C8H9N5)," Acta Crystallogr., C40, 1050‑54 (1984).

J. D. Oliver, D. F. Mullica, David A. Grossie, W. O. Milligan, and H. O. Perkins,   "Structure of Trans‑bis‑(dimethylphenylphosphine)‑bis‑(pyrazole)‑platinum, Pt(C3H4N2)[P(CH3)2 (C6H5)]2," Acta Crystallogr., C40, 746‑48 (1984).

David A. Grossie, W. H. Watson, C. Wu, and P. D. Bartlett, "Rel‑(1S,3aR,4R,7S,7aR)­5,6,7,7a‑tetrahydro‑4,7‑methano‑1H‑indene‑1,3a(4H)‑diol, C10H14O2," Acta Crystallogr., C40, 1416‑18 (1984).

D. F. Mullica, W. O. Milligan, David A. Grossie, G. W. Beall, and L. A. Boatner, "Nine‑fold Coordination in LaPO4: Pentagonal Interpenetrating Tetrahedral Polyhedron," Inorg. Chim. Acta, 95, 231‑36 (1984).

D. F. Mullica, W. O. Milligan, J. S. Belew, David A. Grossie, and E. L. Sappenfield, "Ethyl‑1‑ethyl‑7‑methoxy‑3,4‑dioxo‑2‑phenanthrene‑carboxylate, C20H18O5," Acta Crystallogr., C40, 1923‑25 (1984).

D. F. Mullica, David A. Grossie, and L. A. Boatner, "Coordination Geometry and Structural Determinations of SmPO4, EuPO4, and GdPO4," Inorg. Chim. Acta, 109, 105‑10 (1985).

A. G. Pinkus, D. F. Mullica, W. O. Milligan, David A. Grossie, and P. W. Hurd, "Crystal Structure of 2,2‑Diphenylethyl‑2,4,6‑trimethyl‑phenyl Ketone: Kohler's Ketone.  Mechanism of Stereospecific Enolization Reaction with Grignard Reagents," Tetrahedron, 40, 4829‑35 (1985).

D. F. Mullica, David A. Grossie, and L. A. Boatner, "Structural Refinements of Praseodymium and Neodymium Orthophosphate," J. Solid State Chem., 58, 71‑77 (1985).

D. F. Mullica, E. L. Sappenfield, and David A. Grossie, "Crystal Structure of Neodymium and Gadolinium Dihydroxy‑Nitrate, Ln(OH)2 NO3," J. Solid State Chem., 63, 231‑36 (1986).

D. F. Mullica, H. O. Perkins, David A. Grossie, L. A. Boatner, and B. C. Sales, "Structure of Dichromate‑Type Lead Pyrophosphate, Pb2P2O7," J. Solid State Chem., 62, 371‑76 (1986).

D. F. Mullica, David A. Grossie and L. A. Boatner, "Crystal Structure of 1:1 Gadolinium/Ytterbium Orthophosphate," Inorg. Chim. Acta, 118, 173‑76 (1986).

D. F. Mullica, C. K. C. Lok, and David A. Grossie, "A New Nine‑Coordinate System: Pentagonal Interpenetrating Tetrahedral Polyhedron," J. Solid State Chem., 63 (1986).

D. F. Mullica, J. D. Oliver, E. L. Sappenfield, and David A. Grossie, "trans‑Dichloro­(tricyclohexylphosphino)(triphenylphosphino)platinum (II)," Acta Crystallogr., C42, 1695‑1697 (1986).

D. F. Mullica, J. D. Oliver, and David A. Grossie, "Trans‑tricyclohexylphosphino­triethylphosphino Platinum (II) Chloride, C24H48P2Cl2Pt," Acta Crystallogr., C43, 591‑2 (1987).

D. F. Mullica, J. W. Karban, and David A. Grossie, "1,3‑Diphenyl‑2‑ethyl‑1,3‑propane­dione," Acta Crystallogr., C43, 601‑2 (1987).

Joseph E. Bradshaw, David A. Grossie, Donald F. Mullica, and David E. Pennington, "Preparations and Characterizations of 3‑Oxo‑Hexakis‑(2‑Carboxylato-pyridine­O,O)triaquachromium(III) Perchlorates," Inorg. Chim. Acta, 141, 41‑47 (1988).

D. F. Mullica, Herbert O. Perkins, E. L. Sappenfield, and David A. Grossie, "Synthesis and Structural Study of Samarium Hexacyanoferrate(III) tetrahydrate, SmFe(CN)6 *4H2O," J. Solid State Chem., 74, 9‑15 (1988).

C. J. Dymek, David A. Grossie, Albert V. Fratini, and W. Wade Adams, "Hydrogen­bonded Ion‑ion Interactions in a Molten Salt Precursor: The Crystal Structure of 1‑Methyl‑3‑ethylimidizolium Chloride," Technical Report AFWAL‑TR‑88‑4165 (1988).

Kaoru Fuji, Manabu Node, Midori Sai, Eiichi Fujita, Tetsuro Shingu, William H. Watson, David A. Grossie, and Volker Zabel, "Terpenoids. LI. Structures of Antitumor Diterpenoids, Trichorabdals A-E, Isolated from Rabdosia trichocarpa," Chem. Pharm. Bull., 37, 1465-69 (1989).

C. J. Dymek, David A. Grossie, Albert V. Fratini, and W. Wade Adams, "Evidence for the Presence of Hydrogen‑Bonded Ion‑Ion Interactions in a Molten Salt Precursor, 1‑Methyl‑3‑ethylimidizolium Chloride," J. Mol. Struct., 213, 25-34 (1989).

David A. Grossie and William H. Watson, "Nitrato(Triphenylphosphine oxide)Silver(I), Ag(C18H15PO)NO3," Acta Crystallogr. Sec. C, Crystal. Struct. Commun., C45, 1998-2000 (1989).

David A. Grossie, Albert V. Fratini, and W. Wade Adams, "Single‑Crystal Diffraction analysis of 2‑(Trimethylsilylethynyl)‑4‑nitro‑N,N‑dimethylaniline," Technical Report WRDC‑TR‑89‑4120 (1989).

David A. Grossie and Kenneth Turnbull, "5-Hydroxy-5-methylsydno[3,4-a]indole," Acta Crystallogr. Sec. C, Crystal. Struct. Commun., C48, 377-379 (1992).

David A. Grossie and D. M. Ketcha, "1-Benzenesulfonyl-3-methyl-2-oxo-2,3-dihydroindol-3-yl Acetate," Acta Crystallogr. Sec. C, Crystal. Struct. Commun., C48, 1718-20 (1992).

Daniel M. Ketcha, Qin Zhou, and David Grossie, "Manganese(III) Acetate Oxidation of Alkyl Substituted 1-(Phenylsulfonyl)indoles," Synth. Commun., 24, 565-74 (1994)

David A. Grossie, Daniel M. Ketcha, Johyne P. Brooke, Scott A. Jones and Jonathan G. Grieb, "N-(1-Benzenesulfonyl-4-acetylpyrrol-3-yl)acetamide," Acta Crystallogr. Sec. E, Structure Reports, E57, o778-80 (2001)

David A. Grossie, Kenneth Turnbull and Douglas Krein, “3-(2-Bromophenyl)-4-(triisopropylsilyl)sydnone,Acta Crystallogr. Sec. E, Structure Reports, E57, o985-7 (2001)

David A. Grossie, William A. Feld, Bruce A. Reinhardt, David Bernal, Heather Dyar, Ilyas Khan, Jack Koussa, Holly Krall, Ida Kuhr and Jim Sawyer, “Diethyl 2-oxo-4,5-diphenylcyclopentane-1,3-di-carboxylate,” Acta Crystallogr. Sec. E, Structure Reports, E58, o8–o9 (2002) , with.

G. Riddle, David A. Grossie, and K. Turnbull, “A new sydnone structure: 4-(phenylamino)sydno[3,4-a]quinoxaline,” Acta Crystallogr. Sec. E, Structure Reports, E60,o258-o259 (2004), with.

David A. Grossie and W. A. Feld, “Diethyl 4,5-bis(4-bromophenyl)-2-oxo-cyclopentadiene-1,3-dicarboxylate,” Acta Crystallogr. Sec. E, Structure Reports E60, o1017-o1018 (2004)

G. Riddle, David A. Grossie, and K. Turnbull, “3-(2-Biphenyl)sydnone,” Acta Crystallogr. Sec. E, Structure Reports E60, o977-o978 (2004)

G. Riddle, David A. Grossie, and K. Turnbull, “The sydnone compound 4-hydroxy-4-benzylsydno[3,4-a]indole,” Acta Crystallogr. Sec. E, Structure Reports E60, o1568–o1570 (2004)

Xiaoming Hu, David A. Grossie, and Steven R. Higgins, “Growth and dissolution kinetics at the dolomite-water interface: An in-situ scanning probe microscopy study,” American Mineralogist, 90, 963-968 (2005)

David A Grossie, William A Feld, Lawrence Scanlon, Giselle Sandi, and Zdzislaw Wawrzak, “Di-μ -acetone-κ 2O:O-bis[(acetone-κ O)aqualithium(I)] di-μ -acetone-κ 2O:O-bis[diaqualithium(I)] tetrakis{[phthalocyaninato(2-)-κ 4N,N',N'',N''']lithate(I)},” Acta Crystallographica, Section E: Structure Reports Online E62(4),  m827-m829 (2006)

David A.Grossie, David J.Malwitz, Daniel M Ketcha,. “N,N-Dimethyl-1-phenylsulfonyl-1H-pyrrole-3-sulfonamide,” Acta Crystallographica, Section E: Structure Reports Online E62(3), o980-o982 (2006)

David A. Grossie, Matthew van den Eynden, David Postel, and William A.Feld, “1,4-Bis(4-bromophenyl)-2,3-diphenylbenzene,” Acta Crystallographica, Section E: Structure Reports Online E63(1), o284-o286(2007)

David A. Grossie, Lihong Sun and Kenneth Turnbull, “3-(3,5-dimethoxy-2-trimethylsilylphenyl)-4-trimethylsilylsydnone,” Acta Crystallographica, Section E: Structure Reports Online E63, o2042–o2043 (2007)

David A. Grossie, Eric Fossum, Andrea Elsen and Tricia Meyer, “3,5-Difluorophenyl phenyl sulfone,”  Acta Crystallographica, Section E: Structure Reports Online E64,  o2207 (2008)

David A. Grossie, William A. Feld and John Kelley, “1,3-Di-1-adamantylimidazolium (phthalocyaninato)lithium(I) acetone hemisolvate monohydrate,”  Acta Crystallographica, Section E: Structure Reports Online  E65, M72 (2009)

David A. Grossie, Kenneth Turnbull, Sandra Felix-Balderrama; Shravanthi Raghavapuram, “3-(2-Acetamidophenyl)sydnone” Acta Crystallographica, Section E: Structure Reports Online E65(3), o554-o555 (2009)

Grossie, David; Harrison, Leanna; Turnbull, Kenneth, "4-Acetyl-3-[2-(ethoxycarbonyl)phenyl]sydnone" Acta Crystallographica Section E vol. 69 issue 11 November 01, 2013. p. o1662-o1662

Grossie, David; Harrison, Leanna; Turnbull, Kenneth, "3-{5-Bromo-2-[(triphenylphosphanylidene)amino]phenyl}-4,5-dihydro-1,2,3-oxadiazol-3-ylium-5-olate" Acta Crystallographica Section E vol. 69 issue 8 August 01, 2013. p. o1196-o1196

Stahler, Adam C.; Monahan, Jennifer L.; Dagher, Jessica M.; Baker, Joshua D.; Markopoulos, Marjorie M.; Iragena, Diane B.; NeJame, Britney M.; Slaughter, Robert; Felker, Daniel; Burggraf, Larry W.; Isaac, Leon A. C.; Grossie, David; Gagnon, Zofia E.; Sizemore, Ioana E. Pavel, "Evaluating the abnormal ossification in tibiotarsi of developing chick embryos exposed to 1.0 ppm doses of platinum group metals by spectroscopic techniques" Bone (2013), 53(2), 421-429.

Grossie, David; Harrison, Leanna; Turnbull, Kenneth, "4-(2-bromopropionyl)-3-phenylsydnone" Acta Crystallographica Section E vol. 70, o1165-o1166.

Professional Affiliations/Memberships: 

Americal Chemical Society

American Crystallographic Association

International Union of Crystalography

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