Dawn P. Wooley, Ph.D.

Department:
NeuroScience Cell Bio Physio-COSM
Title:
Professor, Neuroscience Cell Biology & Physiology
Address:
Biological Sciences II 143, 3640 Colonel Glenn Hwy., Dayton, OH 45435-0001

Education History

Postdoctoral Fellow; University of Wisconsin, Madison, 1992-1994

  • Mentor: Nobel Laureate Howard M. Temin, Ph.D.
  • Retroviral mutation and recombination
  • Viral vector technology

Ph.D., Virology; Harvard University, 1992

  • Office of Naval Research and Albert J. Ryan Graduate Fellowships
  • Mentor: Ronald C. Desrosiers, Ph.D.
  • Dissertation: Envelope sequence variation and immune selection of simian immunodeficiency virus (SIV) in persistently infected rhesus monkeys.

B.S., Microbiology; Pennsylvania State University, 1986

  • Summa cum laude with Honors in Molecular and Cell Biology
  • Mentor: Richard J. Frisque, Ph.D.
  • Honors Research Project: Analysis of Naturally Occurring BK Virus Variants

Teaching

Virology (MI 4310/7310)
Gene Therapy (MI 7770)
Biological Safety (ANT 4340/6340, MI 6340, EES 4750/6750): Syllabus

Research Statement

At Wright State University, I serve as the principal investigator on projects related to AIDS, viral vectors, and biodefense. Current projects include HIV-1 mutation and recombination, HIV-1 infection of eosinophils, gene therapy for HIV-1, viral vector biosafety, and antiviral nanotechnology. My laboratory consists of areas equipped for modern molecular biology, tissue culture, and biocontainment.

Service

Director of the Master of Science Program in Microbiology & Immunology
Faculty Senator representing the College of Science & Mathematics

Publications

Adelman, Z. N.*, Albritton, L. M., Boris-Lawrie, K., Buchmeier, M. J., Cannon, P., Cho, M., DiGiusto, D., Donahue, J. K., Federoff, H. J., Hammarskjold, M.-L., Hardison, A. D. Hearing, P., Lee, B., Lee, D. A., Porteus, M. H., Ross, L. F., Ross, S. R., Wooley, D. P., Zoloth, L. (2018). Protect NIH's DNA advisory committee. ScienceĀ  26 Oct 2018:Vol. 362, Issue 6413, pp. 409-410. DOI: 10.1126/science.aav2483.

Wooley, D. P., Sharma, P., Weinstein, J. R., Narayan, P. K. L., Schaffer, D. V., & Excoffon, K. J. D. A. (2017). A directed evolution approach to select for novel Adeno-associated virus capsids on an HIV-1 producer T cell line. J. Virol. Methods. 250:47-54.

Wooley, D. P., & Vasanth, S. (2017). Duplex quantitative polymerase chain reaction assay for detection of adenoviral and lentiviral vectors. Applied Biosafety, 22(3):104-113.

Wooley, D. P., & Byers, K. B. (Eds.). (2017). Biological Safety: Principles and Practices (5th ed.). Washington, DC: ASM Press.

Wooley, D. P. (2017). Molecular Agents. In D. P. Wooley & K. B. Byers (Eds.), Biological Safety: Principles and Practices (5th ed., pp. 269-283). Washington, DC: ASM Press.

Wooley, D. P., & Fleming, D. O. (2017). Risk Assessment of Biological Hazards. In D. P. Wooley & K. B. Byers (Eds.), Biological Safety: Principles and Practices (5th ed., pp. 95-104). Washington, DC: ASM Press.

Schlimgen, R., Howard, J., Wooley, D., Thompson, M., Baden, L. R., Yang, O. O., Christiani, D. C., Mostoslavsky, G., Diamond, D. V., Duane, E. G., Byers, K., Winters, T., Gelfand, J. A., Fujimoto, G., Hudson, T. W., Vyas, J. M. (2016). Risks associated with lentiviral vector exposures and prevention strategies. J Occup Environ Med, 58(12), 1159-1166.

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