Robert M Lober, MD, PhD

Title:
Assistant Professor, Pediatrics
Address:
Dayton Children's Hospital, 1 Childrens Plz, Dayton, OH 45404-1873

Education History

Medical School: Medical College of Georgia

Internship: Stanford Hospitals and Clinics, Stanford, California

Residency: Neurosurgery - Stanford Hospitals and Clinics, Stanford, California

Fellowship: Pediatric Neuro-Oncology and Pediatric Neurosurgery - Stanford Hospitals and Clinics, Stanford, California

Professorship: Assistant Clinical Professor in Pediatrics

Research Statement

Neurosurgery

Neuro-Oncology

Publications

1: Hsu CH, Lober RM, Li MD, Partap S, Murphy PA, Barnes PD, Fisher PG, Yeom KW. Decreased tumor apparent diffusion coefficient correlates with objective response of pediatric low-grade glioma to bevacizumab. J Neurooncol. 2015 Mar 11. [Epub ahead of print] PubMed PMID: 25758812.

2: Yeom KW, Lober RM, Nelson MD Jr, Panigrahy A, Blüml S. Citrate concentrations increase with hypoperfusion in pediatric diffuse intrinsic pontine glioma. J Neurooncol. 2015 Apr;122(2):383-9. doi: 10.1007/s11060-015-1726-0. Epub 2015 Feb 11. PubMed PMID: 25670389.

3: Choudhri O, Lober RM, Camara-Quintana J, Yeom KW, Guzman R, Edwards MS. Carbon dioxide laser for corpus callosotomy in the pediatric population. J Neurosurg Pediatr. 2015 Mar;15(3):321-7. doi: 10.3171/2014.10.PEDS13498. Epub 2014 Dec 19. PubMed PMID: 25525931.

4: Yeom KW, Lober RM, Alexander A, Cheshier SH, Edwards MS. Hydrocephalus decreases arterial spin-labeled cerebral perfusion. AJNR Am J Neuroradiol. 2014 Jul;35(7):1433-9. doi: 10.3174/ajnr.A3891. Epub 2014 Mar 20. PubMed PMID: 24651817.

5: Lober RM, Cho YJ, Tang Y, Barnes PD, Edwards MS, Vogel H, Fisher PG, Monje M, Yeom KW. Diffusion-weighted MRI derived apparent diffusion coefficient identifies prognostically distinct subgroups of pediatric diffuse intrinsic pontine glioma. J Neurooncol. 2014 Mar;117(1):175-82. doi: 10.1007/s11060-014-1375-8. Epub 2014 Feb 13. PubMed PMID: 24522717.

6: Singh H, Grobelny BT, Harrop J, Rosen M, Lober RM, Evans J. Endonasal access to the upper cervical spine, part one: radiographic morphometric analysis. J Neurol Surg B Skull Base. 2013 Jun;74(3):176-84. doi: 10.1055/s-0033-1342923. Epub 2013 Apr 1. PubMed PMID: 24436909; PubMed Central PMCID: PMC3709930.

7: Perreault S, Lober RM, Carret AS, Zhang G, Hershon L, Décarie JC, Vogel H, Yeom KW, Fisher PG, Partap S. Surveillance imaging in children with malignant CNS tumors: low yield of spine MRI. J Neurooncol. 2014 Feb;116(3):617-23. doi: 10.1007/s11060-013-1347-4. Epub 2014 Jan 9. PubMed PMID: 24401959.

8: Perreault S, Lober RM, Cheshier S, Partap S, Edwards MS, Yeom KW. Time-dependent structural changes of the dentatothalamic pathway in children
treated for posterior fossa tumor. AJNR Am J Neuroradiol. 2014 Apr;35(4):803-7. doi: 10.3174/ajnr.A3735. Epub 2013 Sep 19. PubMed PMID: 24052507.

9: Yeom KW, Lober RM, Partap S, Telischak N, Tsolinas R, Barnes PD, Edwards MS. Increased focal hemosiderin deposition in pediatric medulloblastoma patients receiving radiotherapy at a later age. J Neurosurg Pediatr. 2013 Nov;12(5):444-51. doi: 10.3171/2013.7.PEDS1330. Epub 2013 Aug 30. PubMed PMID: 23992236.

10: Perreault S, Lober RM, Carret AS, Zhang G, Hershon L, Décarie JC, Yeom K, Vogel H, Fisher PG, Partap S. Relapse patterns in pediatric embryonal central nervous system tumors. J Neurooncol. 2013 Nov;115(2):209-15. doi: 10.1007/s11060-013-1213-4. Epub 2013 Aug 7. PubMed PMID: 23921420.

11: Yeom KW, Mitchell LA, Lober RM, Barnes PD, Vogel H, Fisher PG, Edwards MS. Arterial spin-labeled perfusion of pediatric brain tumors. AJNR Am J Neuroradiol. 2014 Feb;35(2):395-401. doi: 10.3174/ajnr.A3670. Epub 2013 Aug 1. PubMed PMID: 23907239.

12: Yeom KW, Lober RM, Barnes PD, Campen CJ. Reduced cerebral arterial spin-labeled perfusion in children with neurofibromatosis type 1. AJNR Am J
Neuroradiol. 2013 Sep;34(9):1823-8. doi: 10.3174/ajnr.A3649. Epub 2013 Jun 13. PubMed PMID: 23764727.

13: Yeom KW, Lober RM, Andre JB, Fisher PG, Barnes PD, Edwards MS, Partap S. Prognostic role for diffusion-weighted imaging of pediatric optic pathway glioma. J Neurooncol. 2013 Jul;113(3):479-83. doi: 10.1007/s11060-013-1140-4. Epub 2013 May 15. PubMed PMID: 23673514.

14: Yeom KW, Holdsworth SJ, Van AT, Iv M, Skare S, Lober RM, Bammer R. Comparison of readout-segmented echo-planar imaging (EPI) and single-shot EPI in clinical application of diffusion-weighted imaging of the pediatric brain. AJR Am J Roentgenol. 2013 May;200(5):W437-43. doi: 10.2214/AJR.12.9854. PubMed PMID: 23617511.

15: Lober RM. Low grade gliomas of childhood: the actual management. Minerva Pediatr. 2013 Apr;65(2):149-65. PubMed PMID: 23612260.

16: Yeom KW, Mobley BC, Lober RM, Andre JB, Partap S, Vogel H, Barnes PD. Distinctive MRI features of pediatric medulloblastoma subtypes. AJR Am J
Roentgenol. 2013 Apr;200(4):895-903. doi: 10.2214/AJR.12.9249. PubMed PMID: 23521467.

17: Yeom KW, Lober RM, Mobley BC, Harsh G, Vogel H, Allagio R, Pearson M, Edwards MS, Fischbein NJ. Diffusion-weighted MRI: distinction of skull base chordoma from chondrosarcoma. AJNR Am J Neuroradiol. 2013 May;34(5):1056-61, S1. doi: 10.3174/ajnr.A3333. Epub 2012 Nov 1. PubMed PMID: 23124635.

18: Lober RM, Harsh GR 4th. A perspective on craniopharyngioma. World Neurosurg. 2013 May-Jun;79(5-6):645-6. doi: 10.1016/j.wneu.2012.10.064. Epub 2012 Oct 27. PubMed PMID: 23111221.

19: Hayden Gephart MG, Lober RM, Arrigo RT, Zygourakis CC, Guzman R, Boakye M, Edwards MS, Fisher PG. Trends in the diagnosis and treatment of pediatric primary spinal cord tumors. J Neurosurg Pediatr. 2012 Dec;10(6):555-9. doi: 10.3171/2012.9.PEDS1272. Epub 2012 Oct 12. PubMed PMID: 23061821.

20: Lober RM, Fisher PG. 50 years ago in The Journal of Pediatrics: the surgical management of meningoceles and meningomyeloceles. J Pediatr. 2012 Oct;161(4):734. doi: 10.1016/j.jpeds.2012.05.019. PubMed PMID: 22999580.

21: Lober RM, Guzman R, Cheshier SH, Fredrick DR, Edwards MS, Yeom KW. Application of diffusion tensor tractography in pediatric optic pathway glioma. J Neurosurg Pediatr. 2012 Oct;10(4):273-80. doi: 10.3171/2012.7.PEDS1270. Epub 2012 Aug 17. PubMed PMID: 22900485.

Professional Affiliations/Memberships

Membership in the Alpha Omega Alpha Honor Medical Society

Awards/Recognition

Joint Service Achievement Medals in the United States Army

Merck Manual Award for Perfect Grade Point Average in Medical School

Award for Compassionate Care from the Lucile Packard Children's Hospital Oncology Palliative Care Committee

Research Awards from the American Society for Cell Biology, the Biophysical Society, and the San Francisco Neurological Society

Research Funding from the American Heart Association and the National Institutes of Health 

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